Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 11/20 | 0.41 |
| ▸ | TLR4 | O00206 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335092 | 0.75 | NOTUM (0.40) | — | |
| SCHEMBL256723 | 0.72 | MAPT (0.45) | MAPT | |
| SCHEMBL17498074 | 0.72 | NOTUM (0.40) | — | |
| SCHEMBL5542226 | 0.72 | NOTUM (0.40) | — | |
| SCHEMBL8364082 | 0.70 | NOTUM (0.43) | — | |
| SCHEMBL31161534 | 0.69 | S1PR1 (0.36) | — | |
| SCHEMBL27707619 | 0.68 | GRIA1 (0.37) | — | |
| SCHEMBL5248954 | 0.66 | GRIA1 (0.41) | MAPT | |
| Acetic Acid SCHEMBL28293668 | 0.66 | TDP1 (0.42) | FBP1MAPT | |
| SCHEMBL13064016 | 0.65 | NOTUM (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032540-A1 | Process for the preparation of ropinirole | URGUIMA S.A. (ES) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032540-A1 | Process for the preparation of ropinirole | PRLHR, COMT, DRD4 | RXRA 3305/4885PRMT1 176/4885FBP1 3939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.