Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364082 | 0.79 | NOTUM (0.43) | S1PR1S1PR3NOTUM | |
| SCHEMBL5542226 | 0.74 | NOTUM (0.40) | S1PR1S1PR3NOTUM | |
| SCHEMBL29627844 | 0.71 | NOTUM (0.40) | NOTUM | |
| SCHEMBL5335092 | 0.71 | NOTUM (0.40) | NOTUM | |
| SCHEMBL17498074 | 0.71 | NOTUM (0.40) | NOTUM | |
| SCHEMBL27707619 | 0.70 | GRIA1 (0.37) | — | |
| SCHEMBL1030999 | 0.70 | S1PR1 (0.50) | S1PR1S1PR3NOTUM | |
| SCHEMBL14619694 | 0.69 | RXRA (0.46) | — | |
| SCHEMBL19216634 | 0.69 | LMNA (0.42) | — | |
| SCHEMBL13548839 | 0.68 | ADRA1A (0.45) | S1PR1S1PR3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125400-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-05-07 | — | — | US | disclosed |
| WO-2024220937-A2 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125400-A1 | TYK2 DEGRADERS AND USES THEREOF | TYK2, CSNK2A1, CSNK2A2 | S1PR1 3629/4885S1PR3 3749/4885NOTUM 3387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.