Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659662 | 0.84 | GABRP (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2385337 | 0.79 | P2RX3 (0.43) | IKBKBKDM4EALDH1A1GLAGAA | |
| SCHEMBL4039662 | 0.78 | TSHR (0.45) | KDM4EALDH1A1GLAGAAHPGD | |
| Methane SCHEMBL25264890 | 0.77 | NNMT (0.40) | NNMTPARP1PIM1TTKPIM2 | |
| SCHEMBL16120968 | 0.76 | CSNK1A1 (0.44) | IKBKBBTKKDM4EALDH1A1GLA | |
| SCHEMBL584137 | 0.76 | NNMT (0.43) | IKBKBKDM4EALDH1A1GLAGAA | |
| SCHEMBL6527376 | 0.73 | MAPK8 (0.42) | IKBKBBTKNNMT | |
| SCHEMBL16479902 | 0.72 | GABRP (0.41) | IKBKBKDM4EALDH1A1GLAGAA | |
| SCHEMBL16476801 | 0.72 | IKBKB (0.38) | IKBKBKDM4EALDH1A1GLAGAA | |
| SCHEMBL5209725 | 0.72 | PIM1 (0.45) | KDM4EALDH1A1SMN1; SMN2PIM1TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176310-B1 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents | UCB SA (GB) | 2007-02-13 | — | — | US | disclosed |