Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 7/20 | 0.37 |
| ▸ | BRD4 | O60885 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256009 | 0.74 | PNMT (0.49) | TSHRKMT2AALDH1A1HSPA1AMAPT | |
| SCHEMBL9791471 | 0.72 | CREBBP (0.56) | CREBBPBRD4TSHRKMT2AMEN1 | |
| SCHEMBL6028785 | 0.69 | CREBBP (0.34) | CREBBPBRD4TSHRNNMTKMT2A | |
| SCHEMBL20023207 | 0.68 | KDM4E (0.35) | CREBBPTSHRNNMTKMT2AMEN1 | |
| SCHEMBL9336520 | 0.68 | BRD4 (0.34) | CREBBPBRD4NNMTKMT2AMEN1 | |
| SCHEMBL7922397 | 0.68 | GAA (0.47) | CREBBPBRD4TSHRALDH1A1HTR2A | |
| SCHEMBL30101714 | 0.68 | GAA (0.47) | CREBBPBRD4TSHRALDH1A1HTR2A | |
| SCHEMBL2266750 | 0.67 | NNMT (0.34) | CREBBPBRD4TSHRNNMT | |
| SCHEMBL12965849 | 0.66 | AR (0.45) | CREBBPBRD4TSHRNNMTALDH1A1 | |
| SCHEMBL21729487 | 0.65 | NNMT (0.58) | TSHRNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176312-B2 | Kinase inhibitor scaffolds and methods for their preparation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-02-13 | — | — | US | disclosed |