SCHEMBL7922397

SCHEMBL7922397

Cc1ccc2c(c1)CC(C)N2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
HTR5A P47898 1/20 0.39
BRD4 O60885 4/20 0.38
CREBBP Q92793 3/20 0.38
AR P10275 2/20 0.38
TSHR P16473 1/20 0.38
ACHE P22303 1/20 0.38
EP300 Q09472 1/20 0.38
PGR P06401 1/20 0.38
MGAM O43451 2/20 0.38
SI P14410 2/20 0.38
MGAM2 Q2M2H8 2/20 0.38
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30101714 1.00 GAA (0.47) GAALMNAMAPTHTR5ABRD4
SCHEMBL21782466 0.86 ACHE (0.43) GAALMNAMAPTHTR5ABRD4
SCHEMBL7920989 0.86 ACHE (0.43) GAALMNAMAPTHTR5ABRD4
SCHEMBL30499354 0.81 AR (0.40) GAALMNAMAPTHTR5AAR
SCHEMBL20911110 0.81 AR (0.40) GAALMNAMAPTHTR5ABRD4
SCHEMBL13091374 0.81 AR (0.40) GAALMNAMAPTHTR5AAR
SCHEMBL21243002 0.81 AR (0.40) GAALMNAMAPTHTR5AAR
SCHEMBL4133012 0.81 AR (0.40) GAALMNAMAPTHTR5AAR
SCHEMBL12965849 0.80 AR (0.45) GAALMNAMAPTBRD4CREBBP
SCHEMBL23788032 0.78 HTR5A (0.38) GAALMNAMAPTHTR5AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109161028-B Preparation method of photodegradable two-dimensional polymer with cucurbituril as structural unit 四川大学 2020-12-08 CN claimed
US-20260042748-A1 AZETIDINE COMPOUNDS FOR TREATMENT OF HSV ASSEMBLY BIOSCIENCES INC (US) 2026-02-12 US disclosed
CN-116145156-A Indoline compound preparation method based on organic electronic synthesis 六盘水师范学院 2023-05-23 CN disclosed
CN-110437123-B Method for synthesizing optically pure 2-substituted indoline compound through dynamic kinetic resolution 华中师范大学 2023-01-03 CN disclosed
WO-2021083135-A1 Bcl-2 INHIBITORS BEIGENE, LTD. (KY) 2021-05-06 WO disclosed
CN-107793371-B Bromodomain recognition protein inhibitor and preparation method and application thereof 中国科学院上海药物研究所 2020-12-15 CN disclosed
CN-109161028-B Preparation method of photodegradable two-dimensional polymer with cucurbituril as structural unit 四川大学 2020-12-08 CN disclosed
EP-3106453-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND, AND NOVEL METAL-DIAMINE COMPLEX TAKASAGO PERFUMERY CO LTD (JP) 2020-04-08 EP disclosed
CN-107793371-A A kind of bromine domain identification protein inhibitor and its production and use 中国科学院上海药物研究所 2018-03-13 CN disclosed
US-9745229-B2 Method for producing optically active compound, and novel metal-diamine complex TAKASAGO INTERNATIONAL CORPORATION (JP) 2017-08-29 US disclosed
US-20120010247-A1 BICYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-01-12 US disclosed
US-8012959-B2 Diaminopyrimidinecarboxamide derivative ASTELLAS PHARMA INC. (JP) 2011-09-06 US disclosed
EP-2351743-A1 BICYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2011-08-03 EP disclosed
WO-2010050445-A1 BICYCLIC COMPOUND 武田薬品工業株式会社 (JP) 2010-05-06 WO disclosed
US-20090281072-A1 Diaminopyrimidinecarboxamide Derivative ASTELLAS PHARM INC. (JP) 2009-11-12 US disclosed
US-20090143381-A1 MODULATORS OF ATP-BINDING CASSETTE-TRANSPORTERS VERTEX PHARMACEUTICALS INCORPORATED 2009-06-04 US disclosed
US-5047539-A Ultraviolet radiation stabilizers BASF AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0399278-A2 Heterocyclic amidine derivatives BASF Aktiengesellschaft (DE) 1990-11-28 EP disclosed
EP-0002721-B1 PROCESS FOR PREPARING HYDRAZINES BAYER AG (DE) 1981-09-02 EP disclosed
EP-0002721-A2 Process for preparing hydrazines BAYER AG (DE) 1979-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010247-A1 BICYCLIC COMPOUND ACACA, CPT1B, ACACB GAA 1084/4885LMNA 1520/4885MAPT 3578/4885
US-20260042748-A1 AZETIDINE COMPOUNDS FOR TREATMENT OF HSV CXCR1, ZC3HAV1L, ZC3HAV1 GAA 768/4885LMNA 946/4885MAPT 4175/4885
US-20090281072-A1 Diaminopyrimidinecarboxamide Derivative STAT6, STAT4, STAT3 GAA 2744/4885LMNA 4695/4885MAPT 4703/4885
US-20090143381-A1 MODULATORS OF ATP-BINDING CASSETTE-TRANSPORTERS CFTR, ABCB1, ABCC2 GAA 387/4885LMNA 3826/4885MAPT 4483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.