Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.37 |
| ▸ | BRD1 | O95696 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620056 | 0.85 | BRD4 (0.37) | BRD4SRD5A1TSHRKMT2AGAA | |
| SCHEMBL11661537 | 0.72 | SLC18A3 (0.52) | TSHRGAAMAPTLMNAAKR1C3 | |
| SCHEMBL2766491 | 0.72 | SLC18A3 (0.52) | TSHRGAAMAPTLMNAAKR1C3 | |
| SCHEMBL14959525 | 0.68 | BRD4 (0.67) | BRD4SRD5A1TSHRKMT2AGAA | |
| Bicarbonate SCHEMBL7576375 | 0.68 | AKR1C3 (0.57) | GAAMAPTAKR1C3AKR1C1 | |
| SCHEMBL14479769 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL30514948 | 0.67 | BRD4 (0.46) | BRD4SRD5A1DRD2 | |
| SCHEMBL7641524 | 0.66 | GAA (0.46) | BRD4GAAMAPTLMNAAKR1C3 | |
| SCHEMBL9910977 | 0.66 | BRD4 (0.53) | BRD4SRD5A1DRD2LMNA | |
| SCHEMBL14620259 | 0.66 | GAA (0.42) | BRD4SRD5A1TSHRKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003520-A1 | FLUORESCENT DIKETOPYRROLOPYRROLES AND DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-01-11 | — | — | WO | disclosed |