Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620056 | 0.81 | BRD4 (0.37) | GAAMAPTCTRB1GRIN2BBRD4 | |
| SCHEMBL11661537 | 0.76 | SLC18A3 (0.52) | GAAMAPTAKR1C3AKR1C1SLC18A3 | |
| SCHEMBL2766491 | 0.76 | SLC18A3 (0.52) | GAAMAPTAKR1C3AKR1C1SLC18A3 | |
| Bicarbonate SCHEMBL7576375 | 0.72 | AKR1C3 (0.57) | GAAMAPTAKR1C3AKR1C1GRIN2B | |
| SCHEMBL7641524 | 0.70 | GAA (0.46) | GAAMAPTAKR1C3AKR1C1GRIN2B | |
| SCHEMBL11482528 | 0.69 | GAA (0.68) | GAAMAPTAKR1C3AKR1C1BRD4 | |
| SCHEMBL20197630 | 0.69 | GAA (0.68) | GAAMAPTAKR1C3AKR1C1BRD4 | |
| SCHEMBL9541619 | 0.67 | CTRB1 (0.68) | GAAMAPTCTRB1BRD4TSHR | |
| SCHEMBL657291 | 0.67 | CTRB1 (0.68) | GAAMAPTCTRB1BRD4TSHR | |
| SCHEMBL10895189 | 0.67 | AKR1C3 (0.61) | GAAMAPTAKR1C3AKR1C1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003520-A1 | FLUORESCENT DIKETOPYRROLOPYRROLES AND DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-01-11 | — | — | WO | disclosed |