SCHEMBL14620596

SCHEMBL14620596

CCS(=O)(=O)On1c(C=Cc2ccccc2)nc2ccccc2c1=O

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.63
MAPK1 P28482 1/20 0.63
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
MEN1 O00255 6/20 0.56
KMT2A Q03164 6/20 0.56
GFER P55789 1/20 0.56
LMNA P02545 6/20 0.55
TP53 P04637 2/20 0.55
MAPT P10636 1/20 0.55
SMN1; SMN2 Q16637 3/20 0.52
GAA P10253 1/20 0.51
POLB P06746 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9811170 0.84 NPC1 (0.56) KDM4EMAPK1NPC1RAB9AMEN1
SCHEMBL9811167 0.84 NPC1 (0.56) KDM4EMAPK1NPC1RAB9AMEN1
SCHEMBL14588672 0.81 KDM4E (0.64) KDM4EMAPK1NPC1RAB9AMEN1
SCHEMBL14620107 0.79 KDM4E (0.51) KDM4EMEN1KMT2ALMNAL3MBTL1
SCHEMBL14588671 0.78 LMNA (0.60) KDM4EMAPK1NPC1RAB9AMEN1
SCHEMBL14620607 0.78 MEN1 (0.59) KDM4EMAPK1NPC1RAB9AMEN1
SCHEMBL5749492 0.74 NPC1 (1.00) KDM4EMAPK1NPC1RAB9AMEN1
SCHEMBL5749497 0.74 NPC1 (1.00) KDM4EMAPK1NPC1RAB9AMEN1
SCHEMBL14620223 0.73 ALDH1A1 (0.44) MAPK1NPC1RAB9AMEN1KMT2A
SCHEMBL14620227 0.71 CYP1A2 (0.61) KDM4EMAPK1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157205-B2 Intermediate layer composition for multilayer resist process, pattern-forming process using the same, and laminate FUJI PHOTO FILM CO., LTD. (JP) 2007-01-02 US disclosed