Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1638027 | 0.82 | KMO (0.40) | PTGDR2KMOMAPK8LMNAHPGD | |
| SCHEMBL24966778 | 0.69 | CFD (0.50) | ALOX15SLC22A12HSD17B10 | |
| SCHEMBL24076967 | 0.67 | ALOX15 (1.00) | ALOX15LMNAALDH1A1TSHRNPSR1 | |
| SCHEMBL13534132 | 0.67 | ALOX15 (0.56) | ALOX15PTGDR2SLC22A12LMNAHPGD | |
| SCHEMBL14397303 | 0.66 | ALOX15 (0.51) | ALOX15PTGDR2SLC22A12KMOLMNA | |
| SCHEMBL5749373 | 0.66 | PTGDR2 (0.64) | ALOX15PTGDR2 | |
| SCHEMBL24076925 | 0.66 | ALOX15 (0.70) | ALOX15PTGDR2SLC22A12HTTALDH1A1 | |
| SCHEMBL24076920 | 0.66 | ALOX15 (0.70) | ALOX15PTGDR2SLC22A12TSHRL3MBTL1 | |
| SCHEMBL18357443 | 0.66 | HPGD (0.41) | LMNAHPGDHTTHSD17B10KDM4E | |
| SCHEMBL508683 | 0.65 | PTGDR2 (0.46) | ALOX15PTGDR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002293-A2 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-01-04 | — | — | WO | disclosed |