Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 12/20 | 0.56 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.52 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277865 | 0.98 | EPHX1 (0.59) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL28199266 | 0.98 | EPHX1 (0.59) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL8931322 | 0.98 | EPHX1 (0.59) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL3278820 | 0.98 | EPHX1 (0.59) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL3278553 | 0.98 | EPHX1 (0.59) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL3283012 | 0.93 | EPHX1 (0.50) | EPHX1ZDHHC20ZDHHC2CASP2ALOX15 | |
| SCHEMBL3279311 | 0.84 | — | — | |
| SCHEMBL9580786 | 0.81 | EPHX1 (0.54) | EPHX1ZDHHC20ZDHHC2CASP2NAAA | |
| SCHEMBL1005047 | 0.79 | HDAC1 (0.44) | EPHX1ZDHHC20ZDHHC2ALOX15 | |
| SCHEMBL3762004 | 0.79 | EPHX1 (0.57) | EPHX1ZDHHC20ZDHHC2CASP2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650885-A | Preparation method of N-acyl-2-amino acrylate | 新乡学院 | 2023-01-31 | — | — | CN | claimed |
| US-20070113353-A1 | Polymeric Surface Treatment Compositions | THE CLOROX COMPANY | 2007-05-24 | — | — | US | claimed |
| US-7214813-B2 | Preparation of chiral cyclic amino acids and derivatives | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | claimed |
| US-20040242889-A1 | Preparation of chiral cyclic amino acids and derivatives | THE PENN STATE RESEARCH FOUNDATION | 2004-12-02 | — | — | US | claimed |
| WO-2004011414-A1 | E-ISOMERIC β-AROMATIC OR HETEROAROMATIC SUBSTITUTED β-ACYLAMINO-ACRYLATES AND METHODS OF PREPARING THE SAME | DSM IP ASSETS B.V. (NL) | 2004-02-05 | — | — | WO | claimed |
| EP-0705815-B1 | Process for the preparation of N-arylaminoacrylic acid derivatives | BAYER AG (DE) | 1998-01-14 | — | — | EP | claimed |
| US-5672708-A | Process for the preparation of N-arylaminoacrylic acid derivatives and the use of N-arylaminoacrylic acid derivatives thus prepared for the preparation of 4-quinolone-3-carboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-30 | — | — | US | claimed |
| WO-1993001199-A1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-21 | — | — | WO | claimed |
| US-4328364-A | RHODIUM CATALYST | SNAMPROGETTI, S.P.A. (IT) | 1982-05-04 | — | — | US | claimed |
| EP-0031877-A1 | Optically active 1,2-Bis-(diphenylphosphino)-compounds, metal complexes containing them as chiral ligands and their use | Degussa Aktiengesellschaft (DE) | 1981-07-15 | — | — | EP | claimed |
| JP-54154712-A | — | — | None | — | — | JP | disclosed |
| JP-54057490-A | — | — | None | — | — | JP | disclosed |
| CN-118184525-A | Preparation method of N-substituted-2-amino acrylic ester | 武汉轻工大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-115650885-A | Preparation method of N-acyl-2-amino acrylate | 新乡学院 | 2023-01-31 | — | — | CN | disclosed |
| CN-115650885-A | Preparation method of N-acyl-2-amino acrylate | 新乡学院 | 2023-01-31 | — | — | CN | disclosed |
| EP-0031877-A1 | Optically active 1,2-Bis-(diphenylphosphino)-compounds, metal complexes containing them as chiral ligands and their use | Degussa Aktiengesellschaft (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-4194050-A | HYDROGENATING OXIMES HAVING AN ALPHA-HYDROGEN USING A RUTHENIUM CATALYST AND A CARBOXYLIC ANHYDRIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-03-18 | — | — | US | disclosed |
| JP-S54154712-A | PREPARATION OF OPTICALLY ACTIVE OMEGA-CYANO-ALPHA-ACYLAMINO DERIVATIVE | SUMITOMO CHEM CO LTD | 1979-12-06 | — | — | JP | disclosed |
| JP-S5457490-A | ASYMMETRIC HYDROGENATION CATALYST | AJINOMOTO CO INC | 1979-05-09 | — | — | JP | disclosed |
| US-4137417-A | Process for producing an enamide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242889-A1 | Preparation of chiral cyclic amino acids and derivatives | AADAT, PAM, BCAT2 | EPHX1 4177/4885ZDHHC20 4350/4885ZDHHC2 3922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.