Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879779 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4EALOX15TSHRPOLB | |
| SCHEMBL7764777 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRPOLBPKM | |
| SCHEMBL12226357 | 0.82 | MAPT (0.42) | ALDH1A1KDM4EMAPTHTTALOX15 | |
| SCHEMBL3668924 | 0.82 | MAPT (0.46) | ALDH1A1KDM4EMAPTHTTALOX15 | |
| SCHEMBL8742068 | 0.82 | MAPT (0.46) | ALDH1A1KDM4EMAPTHTTALOX15 | |
| SCHEMBL12642825 | 0.81 | L3MBTL1 (0.55) | ALDH1A1KDM4EMAPTHTTALOX15 | |
| SCHEMBL458012 | 0.80 | KDM4E (0.68) | ALDH1A1KDM4ETSHRPOLBPKM | |
| SCHEMBL5307853 | 0.80 | — | — | |
| SCHEMBL2821117 | 0.80 | KDM4E (0.68) | ALDH1A1KDM4ETSHRPOLBPKM | |
| SCHEMBL3624681 | 0.80 | KDM4E (0.68) | ALDH1A1KDM4ETSHRPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151252-B | Iron death inhibitor-diarylamine acetamides | 维泰瑞隆有限公司 | 2024-08-27 | — | — | CN | disclosed |
| WO-2007002481-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | disclosed |