Triaziquone

Triaziquone

SCHEMBL1462397

O=C(O)C(F)(F)F.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.38
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
TP53 P04637 1/20 0.36
STAT3 P40763 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
APAF1 O14727 2/20 0.32
TDP2 O95551 2/20 0.32
NSD2 O96028 2/20 0.32
HKDC1 Q2TB90 2/20 0.32
MAPK1 P28482 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
HIF1A Q16665 1/20 0.31
KMT2A Q03164 2/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL15269829 0.98 DNMT1 (0.37) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL4608905 0.88 DNMT1 (0.43) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL249462 0.87 DNMT1 (0.36) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL2951599 0.87 MAPT (0.39) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL6176213 0.85 CA1 (0.41) DNMT1
Triaziquone SCHEMBL6009839 0.84 DNMT1 (0.34) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL16419 0.84 MAPT (0.42) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL8507558 0.84 DNMT1 (0.41) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL11422311 0.84 MAPT (0.42) DNMT1MAPTHTTTP53STAT3
Triaziquone SCHEMBL6252286 0.84 MAPT (0.37) DNMT1MAPTHTTTP53STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 415 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114122259-A Perovskite thin-film solar cell and preparation method thereof 杭州纤纳光电科技有限公司 2022-03-01 CN claimed
EP-1487804-B1 AMINOINDAZOLE DERIVATIVES AS PROTEIN-KINASE INHIBITORS AVENTIS PHARMA SA (FR) 2014-02-26 EP claimed
JP-4648630-B2 2011-03-09 JP claimed
EP-1513531-B1 BASIC NON-PEPTIDE BRADYKININ ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREFROM MENARINI RICERCHE SPA (IT) 2009-10-21 EP claimed
JP-2005530711-A 2005-10-13 JP claimed
EP-1487804-A2 AMINOINDAZOLE DERIVATIVES AS PROTEIN-KINASE INHIBITORS Aventis Pharma S.A. (FR) 2004-12-22 EP claimed
WO-2003078403-A2 DERIVES D’AMINOINDAZOLES COMME INHIBITEURS DE PROTEINE-KINASE AVENTIS PHARMA S.A. (FR) 2003-09-25 WO claimed
EP-0821674-B1 CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS SEARLE & CO (US) 2003-08-06 EP claimed
US-20020045574-A1 Glycopeptide antibacterial compounds and methods of using same PRINCETON UNIVERSITY 2002-04-18 US claimed
WO-2001081373-A2 GLYCOPEPTIDE ANTIBACTERIAL COMPOUNDS AND METHODS OF USING SAME MERCK & CO., INC. (US) 2001-11-01 WO claimed
EP-0821674-A1 CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS G.D. SEARLE & CO. (US) 1998-02-04 EP claimed
EP-0468998-A1 PEPTIDES HAVING NOVEL POLAR N-TERMINAL GROUPS THE UPJOHN COMPANY (US) 1992-02-05 EP claimed
WO-1990012804-A2 PEPTIDES HAVING NOVEL POLAR N-TERMINAL GROUPS THE UPJOHN COMPANY (US) 1990-11-01 WO claimed
CN-118317949-A Isoindolines as PMS2 inhibitors 奈奥芬莱有限公司 2024-07-09 CN disclosed
CN-118317954-A Indoline as PROTAC compound 奈奥芬莱有限公司 2024-07-09 CN disclosed
CN-118251391-A Benzimidazole carboxylic acids as GLP-1R agonists 拓臻制药公司 2024-06-25 CN disclosed
EP-0259417-A1 RUTHENIUM CATALYST FOR BIARYLIC COUPLING; NEW STEGANOLIDES. UNIV MAINE LE MANS (FR) 1988-03-16 EP disclosed
EP-0239362-A2 Anti-tumor agents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-09-30 EP disclosed
WO-1987005289-A1 RUTHENIUM CATALYST FOR BIARYLIC COUPLING; NEW STEGANOLIDES UNIVERSITE DU MAINE (LE MANS) (FR) 1987-09-11 WO disclosed
US-4460503-A OLIGO AND POLYPEPTIDES INSTITUT PASTEUR (FR) 1984-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045574-A1 Glycopeptide antibacterial compounds and methods of using same FUT6, DAO, B3GAT3 DNMT1 3886/4885MAPT 4812/4885HTT 3754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.