Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624913 | 0.88 | LMNA (0.52) | SMN1; SMN2MAPTGAALMNARXFP1 | |
| SCHEMBL14624173 | 0.86 | GAA (0.48) | SMN1; SMN2MAPTGAALMNARXFP1 | |
| SCHEMBL4512476 | 0.86 | MAPT (0.60) | SMN1; SMN2NPC1TP53RAB9AMAPT | |
| SCHEMBL14624171 | 0.83 | MAPT (0.56) | MAPTGAALMNARXFP1CACNA1G | |
| SCHEMBL14624172 | 0.83 | DRD2 (0.53) | MAPTGAALMNARXFP1CACNA1G | |
| SCHEMBL14624309 | 0.82 | NAMPT (0.45) | SMN1; SMN2MAPTGAALMNARXFP1 | |
| SCHEMBL13757761 | 0.82 | MAPT (0.54) | SMN1; SMN2NPC1TP53RAB9AMAPT | |
| SCHEMBL14624915 | 0.80 | DRD2 (0.49) | MAPTGAALMNARXFP1CACNA1G | |
| Hydrochloric Acid SCHEMBL8479721 | 0.79 | DRD2 (0.50) | GAALMNARXFP1CACNA1GDRD2 | |
| SCHEMBL6407919 | 0.78 | NPC1 (0.76) | SMN1; SMN2NPC1TP53RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003964-A1 | G-PROTEIN COUPLED RECEPTOR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |