Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.76 |
| ▸ | RAB9A | P51151 | 4/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22871620 | 0.88 | SMN1; SMN2 (0.97) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL28506259 | 0.87 | SMN1; SMN2 (1.00) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL22500570 | 0.85 | SMN1; SMN2 (0.76) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL6075470 | 0.84 | SMN1; SMN2 (0.74) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL29524613 | 0.80 | GAA (0.67) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL28106923 | 0.80 | RAB9A (0.70) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL13912 | 0.80 | KMT2A (0.75) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL22500269 | 0.79 | SMN1; SMN2 (0.81) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL1917562 | 0.79 | NPC1 (0.57) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL14624176 | 0.78 | SMN1; SMN2 (0.58) | NPC1RAB9ATP53SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602368-A2 | Cdc25 phosphatase inhibitors | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2005-12-07 | — | — | EP | disclosed |