Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624298 | 0.85 | PTGDR2 (0.43) | PTGDR2ALDH1A1POLBNPSR1TBXA2R | |
| SCHEMBL14624694 | 0.85 | PTGDR2 (0.47) | PTGDR2ALDH1A1POLBTBXA2RPTGDR | |
| SCHEMBL13478767 | 0.84 | PTGDR2 (0.47) | PTGDR2ALDH1A1TBXA2RPTGDRFABP3 | |
| SCHEMBL14625198 | 0.84 | PTGDR2 (0.47) | PTGDR2ALDH1A1TBXA2RPTGDRFABP3 | |
| SCHEMBL14624167 | 0.83 | EGFR (0.43) | PTGDR2ALDH1A1POLBNPSR1FABP3 | |
| SCHEMBL14624592 | 0.83 | PTGDR2 (0.42) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL13478792 | 0.83 | PTGDR2 (0.48) | PTGDR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14624682 | 0.82 | PTGDR2 (0.45) | PTGDR2TBXA2RPTGDRFABP3HDAC1 | |
| SCHEMBL14623711 | 0.81 | PTGDR2 (0.48) | PTGDR2ALDH1A1TBXA2RPTGDRFABP3 | |
| SCHEMBL14623643 | 0.81 | PTGDR2 (0.46) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002181-A2 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | ELI LILLY AND COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |