Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP2 | O95551 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PTPRCAP | Q14761 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438626 | 0.91 | ATM (0.54) | ACHEATMTUBB4ATUBBTUBA3C | |
| Stegane SCHEMBL5014561 | 0.90 | TUBB4A (0.53) | ACHEATMRAD52DRD2DRD1 | |
| Picrostegane SCHEMBL14097820 | 0.90 | TUBB4A (0.53) | ACHEATMRAD52DRD2DRD1 | |
| SCHEMBL9951919 | 0.75 | GSK3B (0.47) | ACHEATMDRD2DRD1HTR2A | |
| SCHEMBL14097830 | 0.71 | CYP3A4 (0.54) | ATMALDH1A1MAPTTUBB4ATUBB | |
| SCHEMBL5014622 | 0.71 | CYP3A4 (0.54) | ATMALDH1A1MAPTTUBB4ATUBB | |
| SCHEMBL28950301 | 0.68 | TUBB4A (0.57) | ATMKDM4EALDH1A1TDP2MAPT | |
| Steganacin SCHEMBL66054 | 0.68 | LMNA (0.57) | ALDH1A1MAPTTUBB4ATUBBTUBA3C | |
| (-)-Steganacin SCHEMBL10065023 | 0.68 | LMNA (0.57) | ALDH1A1MAPTTUBB4ATUBBTUBA3C | |
| Steganacin SCHEMBL14138211 | 0.68 | LMNA (0.57) | ALDH1A1MAPTTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005760-A1 | METHODS OF APPLICATION OF CHEMICAL COMPOUNDS HAVING THERAPEUTIC ACTIVITIES IN TREATING CANCERS | WANG HAIBIN (US) | 2007-01-11 | — | — | WO | disclosed |