Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 16/20 | 0.56 |
| ▸ | HTR2C | P28335 | 15/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14625270 | 0.85 | HTR2A (0.76) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL27895777 | 0.85 | ALDH1A1 (0.57) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL14625157 | 0.84 | ALDH1A1 (0.49) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL4742374 | 0.80 | ALDH1A1 (0.71) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL7031908 | 0.80 | HTR2A (0.63) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL14624544 | 0.80 | HTR2A (0.46) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL14624766 | 0.79 | ALDH1A1 (0.51) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL14045243 | 0.79 | HTR2A (0.54) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL14625133 | 0.79 | HTR2A (0.57) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL14045239 | 0.78 | HTR2A (0.56) | HTR2AHTR2CL3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006926-A2 | NOVEL 2,4-DIANILINOPYRIMIDINE DERIVATIVES, THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND, IN PARTICULAR, AS IKK INHIBITORS | SANOFI-AVENTIS (FR) | 2007-01-18 | — | — | WO | disclosed |