Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417609 | 0.89 | PLK1 (0.35) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14625069 | 0.84 | RAB9A (0.34) | L3MBTL1GAAALDH1A1HDAC11HDAC8 | |
| SCHEMBL1400066 | 0.82 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12417667 | 0.75 | LMNA (0.54) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14639866 | 0.74 | RAB9A (0.46) | L3MBTL1GAAALDH1A1HDAC8HDAC6 | |
| SCHEMBL12809054 | 0.74 | KDM4E (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1889444 | 0.72 | IRAK4 (0.42) | MEN1KMT2ANPC1HPGDRAB9A | |
| SCHEMBL2191224 | 0.72 | HTT (0.41) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12417619 | 0.72 | BRD4 (0.38) | L3MBTL1GAAALDH1A1RAB9A | |
| SCHEMBL14625073 | 0.69 | TAS1R3 (0.36) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1887002-B1 | CARBOXAMIDE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-08-26 | — | — | EP | disclosed |
| WO-2007007905-A2 | CARBOXAMIDE COMPOUND AND USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-18 | — | — | WO | disclosed |