Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.52 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003507 | 0.93 | SIGMAR1 (0.57) | SIGMAR1TMEM97SLC6A12MCHR1CYP1A2 | |
| SCHEMBL8223184 | 0.89 | PRKAA2 (0.54) | SIGMAR1TMEM97SLC6A12MCHR1CYP1A2 | |
| SCHEMBL13003508 | 0.88 | PRKAA2 (0.59) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13003522 | 0.87 | PRKAB2 (0.53) | SMN1; SMN2CYP3A4 | |
| SCHEMBL13391678 | 0.86 | L3MBTL1 (0.58) | L3MBTL1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL8232629 | 0.80 | SIGMAR1 (0.53) | MEN1KMT2ASIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL13003502 | 0.80 | CXCR4 (0.73) | DRD4SIGMAR1SLC6A12 | |
| SCHEMBL8274001 | 0.80 | MEN1 (0.78) | DRD4LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13003264 | 0.80 | SIGMAR1 (0.52) | SIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL13003512 | 0.80 | CCR3 (0.62) | DRD4KMT2ASIGMAR1SLC6A12MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001975-A1 | PIPERIDINE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORPORATION (US) | 2007-01-04 | — | — | WO | disclosed |