Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14625121 | 0.91 | ALDH1A1 (0.45) | MAPTALDH1A1LMNAMAPK1RAB9A | |
| SCHEMBL14624884 | 0.82 | ALDH1A1 (0.49) | MAPTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL5330139 | 0.79 | ACP3 (0.46) | MAPTALDH1A1LMNARAB9ANPSR1 | |
| SCHEMBL14624863 | 0.77 | CYP3A4 (0.58) | MAPTALDH1A1CYP3A4CYP2C19KMT2A | |
| SCHEMBL5296635 | 0.77 | CYP3A4 (0.58) | MAPTALDH1A1CYP3A4CYP2C19KMT2A | |
| SCHEMBL5330899 | 0.76 | ALDH1A1 (0.49) | MAPTALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL5330894 | 0.76 | ALDH1A1 (0.49) | MAPTALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL14624889 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14624818 | 0.75 | ALDH1A1 (0.45) | MAPTALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL14625379 | 0.73 | ALDH1A1 (0.43) | MAPTALDH1A1LMNARAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011910-A2 | CHIRAL AMINE-CATALYZED ASYMMETRIC ADDITION OF CARBON-CENTERED NUCLEOPHILES TO IMINES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-01-25 | — | — | WO | disclosed |