Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15170371 | 0.82 | CES2 (0.48) | ACP3CES2NPSR1ATML3MBTL1 | |
| SCHEMBL15109749 | 0.80 | ATM (0.57) | ACP3CES2NPSR1ATML3MBTL1 | |
| SCHEMBL14625504 | 0.79 | MAPT (0.49) | CES2NPSR1ATML3MBTL1SMN1; SMN2 | |
| SCHEMBL29675834 | 0.76 | CES2 (0.50) | ACP3CES2NPSR1ATML3MBTL1 | |
| SCHEMBL3458826 | 0.76 | CES2 (0.55) | ACP3CES2NPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3447133 | 0.75 | MAPT (0.46) | ACP3CES2NPSR1ATML3MBTL1 | |
| SCHEMBL4748398 | 0.75 | CES2 (0.51) | ACP3CES2NPSR1ATML3MBTL1 | |
| SCHEMBL11103452 | 0.75 | ACP3 (0.55) | ACP3CES2ATML3MBTL1SMN1; SMN2 | |
| SCHEMBL17045033 | 0.75 | SLC6A9 (0.49) | ACP3CES2NPSR1ATML3MBTL1 | |
| SCHEMBL3446393 | 0.75 | GPR139 (0.46) | ACP3CES2NPSR1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011910-A2 | CHIRAL AMINE-CATALYZED ASYMMETRIC ADDITION OF CARBON-CENTERED NUCLEOPHILES TO IMINES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-01-25 | — | — | WO | disclosed |