Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 9/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132033 | 0.89 | L3MBTL1 (0.72) | L3MBTL1LMNAPTBP1HTTKLF5 | |
| SCHEMBL1586868 | 0.83 | L3MBTL1 (0.61) | L3MBTL1LMNAPTBP1HTTKLF5 | |
| SCHEMBL6678035 | 0.82 | LMNA (0.65) | L3MBTL1LMNAPTBP1HTTKLF5 | |
| SCHEMBL1588043 | 0.82 | L3MBTL1 (0.64) | L3MBTL1LMNAPTBP1HTTKLF5 | |
| SCHEMBL12529291 | 0.82 | L3MBTL1 (0.60) | L3MBTL1LMNAPTBP1HTTKLF5 | |
| SCHEMBL12529828 | 0.82 | NPC1 (0.62) | L3MBTL1LMNAPTBP1HTTKLF5 | |
| SCHEMBL12124292 | 0.81 | NPC1 (0.57) | L3MBTL1LMNAHTTSMN1; SMN2RAB9A | |
| SCHEMBL23091265 | 0.81 | HDAC3 (0.74) | L3MBTL1LMNAPTBP1HTTKLF5 | |
| SCHEMBL30501748 | 0.81 | HDAC3 (0.74) | L3MBTL1LMNAPTBP1HTTKLF5 | |
| SCHEMBL10160826 | 0.81 | NPC1 (0.66) | L3MBTL1LMNASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007010954-A1 | THIOPHENE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-01-25 | — | — | WO | disclosed |