Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 3/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132033 | 0.89 | L3MBTL1 (0.72) | LMNASMN1; SMN2PTBP1HTTKLF5 | |
| SCHEMBL14625554 | 0.82 | L3MBTL1 (0.64) | LMNASMN1; SMN2PTBP1HTTKLF5 | |
| SCHEMBL1588043 | 0.82 | L3MBTL1 (0.64) | LMNASMN1; SMN2PTBP1HTTKLF5 | |
| SCHEMBL23091265 | 0.81 | HDAC3 (0.74) | LMNASMN1; SMN2PTBP1HTTKLF5 | |
| SCHEMBL30501748 | 0.81 | HDAC3 (0.74) | LMNASMN1; SMN2PTBP1HTTKLF5 | |
| SCHEMBL1199911 | 0.81 | NPC1 (0.63) | SMN1; SMN2RAB9ANPC1GAAMITF | |
| SCHEMBL1586868 | 0.80 | L3MBTL1 (0.61) | LMNASMN1; SMN2PTBP1HTTKLF5 | |
| SCHEMBL791385 | 0.79 | L3MBTL1 (0.60) | LMNASMN1; SMN2PTBP1HTTKLF5 | |
| SCHEMBL2202547 | 0.79 | L3MBTL1 (0.60) | LMNASMN1; SMN2PTBP1HTTKLF5 | |
| SCHEMBL12529828 | 0.79 | NPC1 (0.62) | LMNASMN1; SMN2PTBP1HTTKLF5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831068-B2 | Containing a 10,13-dioxa-15,18-diazatricyclo(10.6.2.015,20)-icos-1(18)- en-5-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside group | ABBOTT LABORATORIES | 2004-12-14 | — | — | US | disclosed |
| EP-1474431-A2 | MACROLIDE ANTIBACTERIAL COMPOUNDS | Abbott Laboratories (US) | 2004-11-10 | — | — | EP | disclosed |
| US-20040009931-A1 | Macrolide antibacterial compounds | ABBVIE INC. | 2004-01-15 | — | — | US | disclosed |
| US-20030171308-A1 | Macrolide antibacterial compounds | ABBOTT LABORATORIES | 2003-09-11 | — | — | US | disclosed |
| WO-2003068790-A2 | MACROLIDE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009931-A1 | Macrolide antibacterial compounds | MRPL21, RPN1, CASP1 | LMNA 1186/4885SMN1; SMN2 1392/4885PTBP1 1059/4885 |
| US-20030171308-A1 | Macrolide antibacterial compounds | RPN1, MRPL21, CASP1 | LMNA 1145/4885SMN1; SMN2 1325/4885PTBP1 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.