Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14626053 | 0.87 | HTR2C (0.45) | NPY2RHTR1AHTR7HTR2AHTR6 | |
| SCHEMBL14067250 | 0.73 | NOTUM (0.63) | NPY2RSMN1; SMN2ALDH1A1NOTUM | |
| SCHEMBL14626054 | 0.73 | APEX1 (0.44) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL30852680 | 0.72 | ROCK1 (0.44) | ALDH1A1 | |
| SCHEMBL14626247 | 0.71 | GAA (0.46) | HTR1AHTR7ALDH1A1NLRP3 | |
| SCHEMBL14626017 | 0.70 | MAPT (0.47) | SMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL14625894 | 0.70 | L3MBTL1 (0.54) | HTR1AHTR2ASMN1; SMN2AVPR1AHTR2C | |
| SCHEMBL223608 | 0.70 | MEN1 (0.54) | SMN1; SMN2ALDH1A1L3MBTL1NOTUMMAPT | |
| SCHEMBL14626443 | 0.68 | KMT2A (0.46) | SMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL10267244 | 0.68 | NOTUM (0.54) | HTR2ASMN1; SMN2HTR2CCHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |