Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14625869 | 0.90 | HRH3 (0.43) | HRH3MGLLABHD6KDM4EALDH1A1 | |
| SCHEMBL17324776 | 0.81 | HRH3 (0.47) | ROCK1HRH3CHRNB2CHRNA4 | |
| SCHEMBL20250850 | 0.79 | HRH3 (0.56) | ROCK1HRH3MGLLABHD6KDM4E | |
| SCHEMBL8614407 | 0.79 | ROCK1 (0.54) | ROCK1HRH3MGLLABHD6KDM4E | |
| SCHEMBL17321532 | 0.78 | HRH3 (0.44) | ROCK1HRH3MGLLABHD6KDM4E | |
| SCHEMBL14625867 | 0.72 | NPY2R (0.42) | ALDH1A1 | |
| SCHEMBL23448761 | 0.72 | HTR1B (0.43) | HRH3KDM4EALDH1A1 | |
| SCHEMBL14590673 | 0.71 | NOTUM (0.64) | HRH3KDM4EALDH1A1KMT2A | |
| SCHEMBL6141581 | 0.71 | HTR1A (0.44) | HRH3MGLLABHD6KDM4EALDH1A1 | |
| SCHEMBL5905888 | 0.70 | HRH3 (0.64) | HRH3KDM4ECHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598586-A1 | DRUG LINKERS AND ANTIBODY CONJUGATES THEREOF | Ambrx, Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024077277-A1 | DRUG LINKERS AND ANTIBODY CONJUGATES THEREOF | AMBRX, INC. (US) | 2024-04-11 | — | — | WO | disclosed |