Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GNA15 | P30679 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565827 | 0.90 | ADRB2 (0.43) | FFAR1SRD5A2FFAR4MMP9MMP8 | |
| SCHEMBL14045408 | 0.90 | FFAR1 (0.55) | FFAR1SRD5A2FFAR4LMNAL3MBTL1 | |
| SCHEMBL14155073 | 0.89 | MMP9 (0.44) | FFAR1MMP9MMP8MMP14 | |
| SCHEMBL14565792 | 0.89 | MMP9 (0.44) | FFAR1MMP9MMP8MMP14 | |
| SCHEMBL14021662 | 0.83 | ITGB3 (0.49) | FFAR1SRD5A2MMP9MMP8MMP14 | |
| SCHEMBL4597076 | 0.83 | ITGB3 (0.49) | FFAR1SRD5A2MMP9MMP8MMP14 | |
| SCHEMBL14021677 | 0.82 | FFAR1 (0.57) | FFAR1SRD5A2FFAR4LMNAL3MBTL1 | |
| SCHEMBL14115836 | 0.82 | FFAR1 (0.57) | FFAR1SRD5A2FFAR4LMNAL3MBTL1 | |
| SCHEMBL14045310 | 0.81 | ADRB2 (0.44) | FFAR1SRD5A2FFAR4MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL4596957 | 0.81 | FFAR1 (0.56) | FFAR1SRD5A2FFAR4LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005774-A2 | NOVEL DERIVATIVES OF AMINO ACIDS FOR TREATMENT OF OBESITY AND RELATED DISORDERS | BEXEL PHARMACEUTICALS, INC. (US) | 2007-01-11 | — | — | WO | disclosed |