Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19608875 | 0.84 | ESR2 (0.56) | ABHD6ALDH1A1CYP3A4CYP2C9HPGD | |
| SCHEMBL14591318 | 0.83 | NOTUM (0.65) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL30726807 | 0.83 | ALDH1A1 (0.51) | RAB9ANPC1SMN1; SMN2ABHD6ALDH1A1 | |
| SCHEMBL6341159 | 0.82 | HPGD (0.51) | RAB9ANPC1SMN1; SMN2ABHD6ALDH1A1 | |
| SCHEMBL14591323 | 0.81 | ALDH1A1 (0.50) | RAB9ANPC1SMN1; SMN2ABHD6ALDH1A1 | |
| SCHEMBL30056523 | 0.81 | NOTUM (0.67) | RAB9ANPC1SMN1; SMN2ABHD6ALDH1A1 | |
| SCHEMBL464005 | 0.81 | NOTUM (0.67) | RAB9ANPC1SMN1; SMN2ABHD6ALDH1A1 | |
| SCHEMBL14591400 | 0.79 | TMEM97 (0.55) | ABHD6CYP2C19TMEM97SIGMAR1DRD2 | |
| SCHEMBL14591488 | 0.79 | DRD2 (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL6097273 | 0.79 | NOTUM (0.58) | RAB9ANPC1SMN1; SMN2ABHD6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130149281-A1 | ORGANIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2013-06-13 | — | — | US | disclosed |
| US-7157463-B2 | Substituted piperidines/piperazines as melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130149281-A1 | ORGANIC COMPOUNDS AND THEIR USES | OAT, HAVCR2, CPT1A | RAB9A 3121/4885NPC1 27/4885SMN1; SMN2 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.