Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | ACTR2 | P61160 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14591784 | 0.89 | ALDH1A1 (0.37) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL14591775 | 0.80 | KDM4E (0.47) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL14626859 | 0.80 | PTGER3 (0.39) | CCR2SLC22A12 | |
| SCHEMBL14626852 | 0.78 | IDO1 (0.36) | MEN1KMT2APOLBIDO1TDO2 | |
| SCHEMBL14627047 | 0.76 | ITGB1 (0.45) | MEN1KMT2APOLBRAB9AIDO1 | |
| SCHEMBL14626862 | 0.73 | MAPT (0.49) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL14626706 | 0.71 | ITGB1 (0.57) | IDO1TDO2HDAC6 | |
| SCHEMBL14626864 | 0.70 | MAPT (0.53) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL14626964 | 0.70 | MAPT (0.47) | ALDH1A1MEN1KMT2APOLBNPC1 | |
| SCHEMBL14626858 | 0.69 | ITGB1 (0.45) | MEN1KMT2APOLBRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |