Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14591793 | 0.88 | MAPT (0.48) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL14626862 | 0.85 | MAPT (0.49) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL14626639 | 0.81 | KMT2A (0.52) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL14626707 | 0.78 | MAPT (0.51) | MAPTPOLBMEN1KMT2AABCG2 | |
| SCHEMBL14626967 | 0.76 | MAPT (0.73) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL14626962 | 0.75 | POLB (0.63) | MAPTPOLBMEN1KMT2AABCG2 | |
| SCHEMBL14591788 | 0.73 | MAPT (0.46) | MAPTMEN1KMT2ANPC1CASP3 | |
| SCHEMBL14626964 | 0.73 | MAPT (0.47) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL9825123 | 0.72 | NFE2L2 (0.49) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8494191 | 0.71 | KMT2A (0.73) | MAPTPOLBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |