Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14591788 | 0.87 | MAPT (0.46) | MAPTMEN1KMT2ANPC1CASP3 | |
| SCHEMBL14626864 | 0.85 | MAPT (0.53) | MAPTMEN1KMT2ANPC1CASP3 | |
| SCHEMBL14626639 | 0.84 | KMT2A (0.52) | MAPTMEN1KMT2ANPC1CASP3 | |
| SCHEMBL14626967 | 0.79 | MAPT (0.73) | MAPTMEN1KMT2ANPC1CASP3 | |
| SCHEMBL14626709 | 0.76 | IMPDH2 (0.43) | MAPTMEN1KMT2AALDH1A1IMPDH2 | |
| SCHEMBL14626964 | 0.76 | MAPT (0.47) | MAPTMEN1KMT2ANPC1CASP3 | |
| SCHEMBL14591793 | 0.73 | MAPT (0.48) | MAPTMEN1KMT2ANPC1CASP3 | |
| SCHEMBL8494188 | 0.73 | KMT2A (0.73) | MAPTMEN1KMT2ANPC1CASP3 | |
| SCHEMBL8494191 | 0.73 | KMT2A (0.73) | MAPTMEN1KMT2ANPC1CASP3 | |
| SCHEMBL14626638 | 0.73 | ALDH1A1 (0.39) | MAPTMEN1KMT2ANPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |