SCHEMBL1462669

SCHEMBL1462669

CCCC(=O)C(=O)CCC(C)(C)C

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES2 O00748 7/20 0.63
CES1 P23141 7/20 0.63
HDAC3 O15379 4/20 0.43
HDAC1 Q13547 4/20 0.43
HDAC2 Q92769 4/20 0.43
HDAC8 Q9BY41 4/20 0.43
FFAR3 O14843 3/20 0.43
TSHR P16473 1/20 0.38
ALDH1A1 P00352 2/20 0.36
HDAC6 Q9UBN7 1/20 0.35
CTSD P07339 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108642 0.80 CES1 (1.00) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL16940468 0.79 CES1 (0.63) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL10014775 0.79 CES2 (0.41) CES2CES1HDAC3HDAC1HDAC2
Butyric Acid SCHEMBL4631705 0.77 FFAR3 (0.65) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL8420717 0.76 OR51E2 (0.46) CES2CES1TSHRALDH1A1
SCHEMBL25670656 0.76 CES1 (0.46) CES2CES1TSHRALDH1A1CA1
SCHEMBL8873751 0.74 OR51E2 (0.43) TSHRALDH1A1
SCHEMBL8873753 0.74 CA4 (0.36) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL22921037 0.74 ALDH1A1 (0.31) ALDH1A1
SCHEMBL28316613 0.74 FAAH (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011028623-A2 MODIFIED ORGANISMS FOR IMPROVED SACCHARIFICATION OF BIOMASS QTEROS, INC. (US) 2011-03-10 WO disclosed