Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436159 | 0.90 | ITGB1 (0.55) | ITGB1ITGA4MEN1KMT2ANPC1 | |
| SCHEMBL14591746 | 0.88 | ITGA4 (0.51) | ITGB1ITGA4MEN1KMT2ANPC1 | |
| SCHEMBL14626637 | 0.88 | NPC1 (0.56) | MEN1KMT2ANPC1NHERF1HRH3 | |
| SCHEMBL2438042 | 0.86 | ITGB1 (0.53) | ITGB1ITGA4MEN1KMT2ANPC1 | |
| SCHEMBL14626746 | 0.86 | HDAC1 (0.43) | ITGB1ITGA4MEN1KMT2ANPC1 | |
| SCHEMBL12327687 | 0.85 | NHERF1 (0.51) | ITGB1ITGA4MEN1KMT2ANPC1 | |
| SCHEMBL14626743 | 0.85 | KMT2A (0.68) | MEN1KMT2ANPC1HRH3CFTR | |
| SCHEMBL92581 | 0.82 | RAB9A (0.64) | MEN1KMT2ANPC1NHERF1CFTR | |
| SCHEMBL14626642 | 0.81 | CFTR (0.65) | MEN1KMT2ANPC1NHERF1HRH3 | |
| SCHEMBL14626745 | 0.80 | NPC1 (0.55) | MEN1KMT2ANPC1NHERF1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |