Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14591786 | 0.86 | MEN1 (0.49) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL14626967 | 0.84 | MAPT (0.73) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL14626862 | 0.84 | MAPT (0.49) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL14626864 | 0.81 | MAPT (0.53) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL2604917 | 0.79 | ALDH1A1 (0.61) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL27906936 | 0.79 | ALDH1A1 (0.61) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL8494188 | 0.76 | KMT2A (0.73) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL8494191 | 0.76 | KMT2A (0.73) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL14756766 | 0.75 | MAPT (0.71) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL14626964 | 0.74 | MAPT (0.47) | KMT2AMEN1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |