SCHEMBL14627720

SCHEMBL14627720

N=c1ccc2c(-c3ccc(C(=O)O)cc3C(=O)O)c3ccc(N)cc3oc-2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.63
USP2 O75604 4/20 0.61
ATM Q13315 2/20 0.61
CFTR P13569 1/20 0.61
PAX8 Q06710 1/20 0.61
GOPC Q9HD26 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.59
MEN1 O00255 2/20 0.42
POLB P06746 2/20 0.42
KMT2A Q03164 2/20 0.42
ALPL P05186 1/20 0.42
ALPI P09923 1/20 0.42
ALPG P10696 1/20 0.42
CA9 Q16790 11/20 0.42
CA1 P00915 9/20 0.39
CA2 P00918 9/20 0.39
CA12 O43570 3/20 0.37
DNASE1L3 Q13609 1/20 0.36
PRMT1 Q99873 1/20 0.36
FTO Q9C0B1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29483446 1.00 ABCB1 (0.63) ABCB1USP2ATMCFTRPAX8
SCHEMBL12716297 0.93 ABCB1 (0.63) ABCB1USP2ATMCFTRPAX8
SCHEMBL10082964 0.92 ABCB1 (0.59) ABCB1USP2ATMCFTRPAX8
SCHEMBL25717462 0.90 ABCB1 (0.60) ABCB1USP2ATMCFTRPAX8
SCHEMBL25713454 0.90 ABCB1 (0.60) ABCB1USP2ATMCFTRPAX8
SCHEMBL17342806 0.88 ABCB1 (0.58) ABCB1USP2ATMCFTRPAX8
SCHEMBL17342811 0.88 ABCB1 (0.58) ABCB1USP2ATMCFTRPAX8
SCHEMBL12307302 0.88 ABCB1 (0.65) ABCB1USP2ATMCFTRPAX8
SCHEMBL7970059 0.88 USP2 (0.76) ABCB1USP2ATMCFTRPAX8
SCHEMBL458205 0.88 ABCB1 (0.77) ABCB1USP2ATMCFTRPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023167333-A1 FLUORESCENCE IMAGING OF CANCER CELLS 国立大学法人 東京大学 2023-09-07 WO disclosed
WO-2023167333-A1 FLUORESCENCE IMAGING OF CANCER CELLS 国立大学法人 東京大学 2023-09-07 WO disclosed
US-20180052105-A1 SULFANE SULFUR-SELECTIVE FLUORESCENT PROBE THE UNIVERSITY OF TOKYO (JP) 2018-02-22 US disclosed
US-20180052105-A1 SULFANE SULFUR-SELECTIVE FLUORESCENT PROBE THE UNIVERSITY OF TOKYO (JP) 2018-02-22 US disclosed
US-20170045525-A1 GLUTATHIONE-DETECTING FLUORESCENT PROBE THE UNIVERSITY OF TOKYO (JP) 2017-02-16 US disclosed
US-20170045525-A1 GLUTATHIONE-DETECTING FLUORESCENT PROBE THE UNIVERSITY OF TOKYO (JP) 2017-02-16 US disclosed
US-9068985-B2 Fluorescent labeling of living cells EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-06-30 US disclosed
US-20140206840-A1 FLUORESCENT LABELING OF LIVING CELLS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-07-24 US disclosed
US-7157572-B2 UV excitable energy transfer reagents APPLERA CORPORATION (US) 2007-01-02 US disclosed