SCHEMBL7970059

SCHEMBL7970059

Nc1ccc2c(-c3ccc(C(=O)O)cc3C(=O)O)c3ccc(=O)cc-3oc2c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 4/20 0.76
L3MBTL1 Q9Y468 1/20 0.76
MEN1 O00255 2/20 0.55
POLB P06746 2/20 0.55
KMT2A Q03164 2/20 0.55
ALPL P05186 1/20 0.55
ALPI P09923 1/20 0.55
ALPG P10696 1/20 0.55
CA9 Q16790 13/20 0.52
CA1 P00915 11/20 0.49
CA2 P00918 11/20 0.49
ABCB1 P08183 1/20 0.48
ATM Q13315 2/20 0.47
PLEC Q15149 1/20 0.47
CA12 O43570 4/20 0.47
DNASE1L3 Q13609 1/20 0.47
PRMT1 Q99873 1/20 0.47
CFTR P13569 1/20 0.47
PAX8 Q06710 1/20 0.47
GOPC Q9HD26 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7959938 0.92 USP2 (0.68) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL29483446 0.88 ABCB1 (0.63) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL14627720 0.88 ABCB1 (0.63) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL1437042 0.87 USP2 (0.78) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL3430200 0.87 USP2 (0.74) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL3481432 0.86 USP2 (1.00) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL30023431 0.86 USP2 (1.00) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL7973529 0.85 USP2 (0.59) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL3658646 0.85 FTO (0.58) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL12238062 0.85 USP2 (0.57) USP2L3MBTL1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023167333-A1 FLUORESCENCE IMAGING OF CANCER CELLS 国立大学法人 東京大学 2023-09-07 WO disclosed
US-6229055-B1 SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES MOLECULAR PROBES, INC. 2001-05-08 US disclosed
US-6162931-A Fluorinated xanthene derivatives MOLECULAR PROBES, INC. (US) 2000-12-19 US disclosed