Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 3/20 | 0.63 |
| ▸ | CFTR | P13569 | 1/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 12/20 | 0.38 |
| ▸ | CA1 | P00915 | 10/20 | 0.38 |
| ▸ | CA2 | P00918 | 9/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17695458 | 0.93 | ABCB1 (0.61) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL14176752 | 0.89 | ABCB1 (0.62) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL14627720 | 0.88 | ABCB1 (0.63) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL29483446 | 0.88 | ABCB1 (0.63) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL12716297 | 0.87 | ABCB1 (0.63) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL458205 | 0.87 | ABCB1 (0.77) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL23378600 | 0.86 | ABCB1 (0.64) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL19269176 | 0.86 | ABCB1 (0.62) | ABCB1USP2CFTRPAX8ATM | |
| Hydrochloric Acid SCHEMBL5606345 | 0.86 | USP2 (0.76) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL7006557 | 0.86 | ABCB1 (0.50) | ABCB1USP2CFTRPAX8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170240570-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2017-08-24 | — | — | US | disclosed |
| US-20170082642-A1 | FLUORESCENT CELL MARKERS | KODE BIOTECH LTD (NZ) | 2017-03-23 | — | — | US | disclosed |
| US-20110229980-A1 | OLIGONUCLEOTIDE PROBE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2011-09-22 | — | — | US | disclosed |
| EP-1573068-B1 | HETEROCYCLIC FRET DYE CASSETTES FOR LABELING BIOLOGICAL MOLECULES AND THEIR USE IN DNA SEQUENCING | GE HEALTHCARE BIO SCIENCES (US) | 2010-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170082642-A1 | FLUORESCENT CELL MARKERS | PTDSS2, SPTLC2, CD69 | ABCB1 3932/4885USP2 1329/4885CFTR 3824/4885 |
| US-20110229980-A1 | OLIGONUCLEOTIDE PROBE AND USE THEREOF | DCLRE1B, NSUN2, MTX2 | ABCB1 560/4885USP2 2107/4885CFTR 954/4885 |
| US-20170240570-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | MKI67, TP53, PCNA | ABCB1 1599/4885USP2 1953/4885CFTR 3595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.