Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 18/20 | 0.59 |
| ▸ | WDR77 | Q9BQA1 | 18/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADK | P55263 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13483564 | 0.92 | PRMT5 (0.68) | PRMT5WDR77ADORA2AADK | |
| SCHEMBL13867345 | 0.90 | PRMT5 (0.57) | PRMT5WDR77ADORA2AADK | |
| SCHEMBL4797267 | 0.89 | PRMT5 (0.55) | PRMT5WDR77ADORA2AADK | |
| SCHEMBL13864255 | 0.89 | PRMT5 (0.56) | PRMT5WDR77ADORA2AADK | |
| SCHEMBL13482921 | 0.89 | PRMT5 (0.56) | PRMT5WDR77ADORA2AADK | |
| Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14628542 | 0.88 | ADORA2A (0.67) | PRMT5WDR77ADORA2AADK | |
| Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14628545 | 0.88 | ADORA2A (0.67) | PRMT5WDR77ADORA2AADK | |
| Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL733423 | 0.88 | ADORA2A (0.67) | PRMT5WDR77ADORA2AADK | |
| Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL12150774 | 0.88 | ADORA2A (0.67) | PRMT5WDR77ADORA2AADK | |
| Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL6422519 | 0.88 | ADORA2A (0.67) | PRMT5WDR77ADORA2AADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157434-B2 | Nucleoside compounds for treating viral infections | GENELABS TECHNOLOGIES, INC. (US) | 2007-01-02 | — | — | US | disclosed |