Beta-2'-C-Methyl-7-Deaza-Adenosine

Beta-2'-C-Methyl-7-Deaza-Adenosine

SCHEMBL14628545

C[C@@]1(O)C(O)C(CO)OC1n1ccc2c(N)ncnc21

nearest known ligand 0.67

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.67
PRMT5 O14744 12/20 0.57
WDR77 Q9BQA1 12/20 0.57
ADK P55263 1/20 0.53
ADORA3 P0DMS8 4/20 0.52
ADA P00813 1/20 0.48
ADORA2B P29275 1/20 0.48
ADORA1 P30542 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL13772636 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL731022 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL12150774 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14628542 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14081715 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL13055908 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL15093204 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL18661674 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14640071 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL6422519 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157434-B2 Nucleoside compounds for treating viral infections GENELABS TECHNOLOGIES, INC. (US) 2007-01-02 US disclosed