Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 3/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809882 | 0.72 | EGFR (0.46) | EGFR | |
| SCHEMBL140301 | 0.72 | EGFR (0.46) | EGFR | |
| SCHEMBL5583902 | 0.71 | CYP11B1 (0.37) | EGFR | |
| SCHEMBL5436850 | 0.71 | KDM4D (0.41) | CTSSCTSK | |
| SCHEMBL4713968 | 0.68 | ALDH1A1 (0.41) | EGFR | |
| SCHEMBL14644325 | 0.68 | EGFR (0.35) | EGFR | |
| SCHEMBL29641000 | 0.68 | HPGDS (0.42) | EGFR | |
| SCHEMBL21379737 | 0.68 | HPGDS (0.42) | EGFR | |
| SCHEMBL31627825 | 0.67 | KDM4E (0.36) | — | |
| SCHEMBL17241197 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739081-A1 | HYDRAZINO-SUBSTITUTED HETEROCYCLIC NITRILE COMPOUNDS AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-03 | — | — | EP | disclosed |