Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14377125 | 0.85 | PNMT (0.40) | HTR2AHTR2CHTR2BDRD2DRD3 | |
| SCHEMBL16195986 | 0.72 | ITGB3 (0.40) | — | |
| SCHEMBL5432327 | 0.71 | — | — | |
| SCHEMBL14629279 | 0.71 | NOX1 (0.37) | HTR2AHTR2CHTR2BMETSOS2 | |
| SCHEMBL12101153 | 0.69 | PNMT (0.49) | HTR2AHTR2CHTR2BDRD2DRD3 | |
| SCHEMBL7513380 | 0.65 | — | — | |
| SCHEMBL15321365 | 0.64 | PNMT (0.36) | PNMT | |
| SCHEMBL2161648 | 0.64 | PNMT (0.34) | HTR2AHTR2CHTR2BPNMT | |
| SCHEMBL14629348 | 0.63 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL26671809 | 0.63 | XIAP (0.44) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739081-A1 | HYDRAZINO-SUBSTITUTED HETEROCYCLIC NITRILE COMPOUNDS AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-03 | — | — | EP | disclosed |