Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.31 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16195986 | 0.83 | ITGB3 (0.40) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL18183649 | 0.68 | KDM4E (0.44) | HTR2AHTR2C | |
| SCHEMBL2960628 | 0.68 | SMN1; SMN2 (0.47) | HTR2AHTR2C | |
| SCHEMBL29740385 | 0.68 | SMN1; SMN2 (0.47) | HTR2AHTR2C | |
| SCHEMBL14377125 | 0.66 | PNMT (0.40) | HTR2AHTR2CHTR2B | |
| SCHEMBL4204764 | 0.65 | HTR2C (0.44) | HTR2AHTR2CHTR2B | |
| SCHEMBL19239790 | 0.64 | SOS2 (0.36) | HTR2AHTR2CHTR2B | |
| SCHEMBL14629356 | 0.63 | HTR2A (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL22049112 | 0.63 | OGA (0.36) | — | |
| SCHEMBL12101153 | 0.63 | PNMT (0.49) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739081-A1 | HYDRAZINO-SUBSTITUTED HETEROCYCLIC NITRILE COMPOUNDS AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-03 | — | — | EP | disclosed |