SCHEMBL14629609

SCHEMBL14629609

CCCC(CC)(Oc1ccc(C2(c3ccc(Oc4cccc(C(C)(Cl)CC)c4C#N)cc3)c3ccccc3-c3ccccc32)cc1)c1cccc(Cl)c1C#N

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
HSD11B1 P28845 1/20 0.34
TLR8 Q9NR97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14640016 0.95 MAPT (0.38) MAPTHSD11B1TLR8
SCHEMBL12872669 0.82 MAPT (0.38) MAPTHSD11B1TLR8
SCHEMBL13298968 0.77 MAPT (0.38) MAPTHSD11B1TLR8
SCHEMBL19322845 0.76 MCL1 (0.33) HSD11B1
SCHEMBL14277011 0.76
SCHEMBL12433514 0.76 MAPT (0.50) MAPTHSD11B1TLR8
SCHEMBL14629708 0.74 HSD11B1 (0.36) MAPTHSD11B1TLR8
SCHEMBL14264198 0.74 MAPT (0.43) MAPTHSD11B1TLR8
SCHEMBL13250812 0.74 MAPT (0.43) MAPTHSD11B1TLR8
SCHEMBL15759858 0.73 AR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070015041-A1 Membrane-electrode assemblies JSR CORPORATION 2007-01-18 US disclosed