SCHEMBL19322845

SCHEMBL19322845

CCC(C)(C)Oc1ccc(C2(c3ccc(Oc4cccc(C(C)(C)CC)c4C#N)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.33
MEN1 O00255 1/20 0.32
CNR1 P21554 1/20 0.32
GPR183 P32249 1/20 0.32
CNR2 P34972 1/20 0.32
KMT2A Q03164 1/20 0.32
AR P10275 4/20 0.32
SLC6A4 P31645 1/20 0.31
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15759858 0.88 AR (0.31) MCL1MEN1CNR1GPR183CNR2
SCHEMBL14640016 0.79 MAPT (0.38) MCL1MEN1CNR1GPR183CNR2
SCHEMBL15869189 0.78 MEN1 (0.46) MEN1KMT2A
SCHEMBL19322843 0.78 GRM2 (0.36) MCL1MEN1CNR1GPR183CNR2
SCHEMBL15760408 0.77 ESR1 (0.40) MEN1KMT2AARSLC6A4HSD11B1
SCHEMBL14629609 0.76 MAPT (0.34) HSD11B1
SCHEMBL18179357 0.75 SMN1; SMN2 (0.35) MCL1MEN1KMT2AARSLC6A4
SCHEMBL21183502 0.75 NPC1 (0.43) MCL1MEN1KMT2A
SCHEMBL12906760 0.75 NPC1 (0.31) MEN1CNR1GPR183CNR2KMT2A
SCHEMBL18179336 0.74 SMN1; SMN2 (0.34) MCL1MEN1KMT2AARSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10253210-B2 Film-forming composition including thermosetting resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-04-09 US disclosed
US-20170253764-A1 FILM-FORMING COMPOSITION INCLUDING THERMOSETTING RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-09-07 US disclosed