Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3748563 | 0.81 | MAOB (0.61) | SMN1; SMN2PKMMAOBHTR1AADORA3 | |
| SCHEMBL4445212 | 0.69 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1ADORA3CYP2C9 | |
| SCHEMBL8185857 | 0.68 | KDM4E (0.46) | SMN1; SMN2KDM4EALDH1A1ADORA3PDE4A | |
| SCHEMBL3228294 | 0.68 | ATM (0.46) | MAPK1ALDH1A1TP53MAPTHTT | |
| SCHEMBL3235516 | 0.67 | SMN1; SMN2 (0.49) | SMN1; SMN2PKMMAOBALDH1A1TP53 | |
| SCHEMBL2541031 | 0.67 | ADORA3 (0.38) | MAOBHTR1AADORA3CYP2C9PDE4A | |
| SCHEMBL8190562 | 0.65 | ALDH1A1 (0.67) | KDM4EHSD17B10GAAMAPK1ALDH1A1 | |
| SCHEMBL8705605 | 0.65 | HSP90AA1 (0.52) | SMN1; SMN2KDM4EGAAMAPK1ALDH1A1 | |
| SCHEMBL16641094 | 0.65 | CYP19A1 (0.77) | KDM4EALDH1A1MAPTHSP90AA1KMT2A | |
| SCHEMBL7443281 | 0.65 | CNOT7 (0.46) | PDE4AADORA2APDE4DHSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1738766-A1 | PREVENTIVE AND/OR THERAPEUTIC AGENT FOR DISEASE ACCOMPANIED BY CHRONIC MUSCLE/SKELETON PAIN | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-01-03 | — | — | EP | disclosed |