Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.46 |
| ▸ | PARN | O95453 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984842 | 0.82 | CNOT7 (0.54) | CNOT7PARNADORA2AMEN1KMT2A | |
| SCHEMBL2993196 | 0.81 | CNOT7 (0.53) | CNOT7PARNADORA2AMEN1KMT2A | |
| SCHEMBL13861874 | 0.80 | CNOT7 (0.70) | CNOT7PARNADORA2AMEN1KMT2A | |
| SCHEMBL7985247 | 0.78 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1FYNMEN1KMT2A | |
| SCHEMBL10812168 | 0.78 | PDE4A (0.53) | CNOT7PARNPDE4APDE4BPDE4C | |
| SCHEMBL9844553 | 0.74 | PDE4A (0.56) | CNOT7PARNPDE4APDE4BPDE4C | |
| SCHEMBL27461932 | 0.72 | PDE4A (0.49) | CNOT7PARNPDE4APDE4BPDE4C | |
| SCHEMBL7985241 | 0.71 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL8798601 | 0.71 | CNOT7 (0.76) | CNOT7PARNMEN1KMT2A | |
| SCHEMBL26925735 | 0.70 | CYP3A4 (0.66) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550570-A1 | XANTHINE DERIVATIVES | Beecham Group p.l.c. (GB) | 1993-07-14 | — | — | EP | claimed |
| WO-1992005175-A1 | XANTHINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-04-02 | — | — | WO | claimed |