Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13021112 | 0.98 | TERT (0.54) | TERTHTR1AMAOBDRD2DRD3 | |
| SCHEMBL18969774 | 0.97 | TERT (0.56) | TERTHTR1AMAOBDRD2DRD3 | |
| SCHEMBL2743018 | 0.86 | HPGD (0.61) | — | |
| SCHEMBL12936260 | 0.85 | KDM4E (0.56) | HTR1AMAOB | |
| SCHEMBL6339624 | 0.85 | HTR1A (0.69) | HTR1AMAOBDRD2DRD3 | |
| SCHEMBL1569172 | 0.85 | HTR1A (0.69) | HTR1AMAOBDRD2DRD3 | |
| SCHEMBL29163908 | 0.84 | ALDH1A1 (0.66) | TERTHTR1AMAOB | |
| SCHEMBL30690126 | 0.84 | ALDH1A1 (0.66) | TERTHTR1AMAOB | |
| SCHEMBL7519591 | 0.84 | GAA (0.60) | — | |
| SCHEMBL8862856 | 0.84 | GAA (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071147-A1 | 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | LUK KIN-CHUN | 2011-03-24 | — | — | US | disclosed |
| EP-1917015-A1 | NOVEL 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007019884-A1 | NOVEL 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-22 | — | — | WO | disclosed |
| US-20050256154-A1 | 4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides | LUK KIN-CHUN | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256154-A1 | 4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides | FGFR3, FGFR4, FGFR1 | TERT 1832/4885HTR1A 2177/4885MAOB 2809/4885 |
| US-20110071147-A1 | 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | FGFR3, FGFR4, FGFR1 | TERT 1832/4885HTR1A 2177/4885MAOB 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.