Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | STK10 | O94804 | 2/20 | 0.40 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040632 | 0.82 | PARP1 (0.53) | PARP1MAOAMAOBNPSR1STK10 | |
| SCHEMBL29050703 | 0.76 | MAOA (0.53) | PARP1MAOAMAOBNPSR1STK10 | |
| SCHEMBL5506330 | 0.75 | MAOA (0.51) | PARP1MAOAMAOBNPSR1STK10 | |
| SCHEMBL1356477 | 0.74 | PARP1 (0.45) | PARP1NPSR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28839422 | 0.73 | ALDH1A1 (0.56) | PARP1NPSR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5051981 | 0.72 | PARP1 (0.62) | PARP1NPSR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL30350041 | 0.72 | POLB (0.53) | PARP1MAOAMAOBNPSR1KMT2A | |
| SCHEMBL17948245 | 0.72 | POLB (0.53) | PARP1MAOAMAOBNPSR1KMT2A | |
| SCHEMBL31241414 | 0.71 | CES1 (0.63) | PARP1MAOANPSR1STK10SLK | |
| SCHEMBL3079295 | 0.71 | CES1 (0.63) | PARP1MAOANPSR1STK10SLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130023609-A1 | Use of protected N-hydroxyimide derivates and transition metal as oxygen scavenger system in transparent polyolefin films | BASF SE (DE) | 2013-01-24 | — | — | US | disclosed |