Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.62 |
| ▸ | CTSS | P25774 | 7/20 | 0.62 |
| ▸ | CTSB | P07858 | 4/20 | 0.62 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059680 | 0.89 | CTSS (0.67) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL31380364 | 0.89 | CTSS (0.67) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL3059684 | 0.89 | CTSS (0.67) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL14638337 | 0.88 | CTSK (0.48) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL20905314 | 0.88 | CTSS (0.71) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL27350854 | 0.88 | CTSS (0.71) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL14638520 | 0.87 | CTSK (0.48) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL2346583 | 0.87 | CTSS (0.69) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL21946642 | 0.87 | CTSS (0.69) | CTSKCTSSCTSBCTSLACE | |
| SCHEMBL29657242 | 0.87 | CTSS (0.69) | CTSKCTSSCTSBCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | CTSK 298/4885CTSS 277/4885CTSB 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.