Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.48 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705633 | 1.00 | ACE (0.48) | ACEDPP4DPP8ANPEPPOLB | |
| SCHEMBL14634965 | 1.00 | ACE (0.48) | ACEDPP4DPP8ANPEPPOLB | |
| SCHEMBL18031566 | 0.79 | KEAP1 (0.56) | ACEPOLBTDP1PREPL3MBTL1 | |
| SCHEMBL14194351 | 0.78 | DPP8 (0.56) | DPP4DPP8PARP1 | |
| SCHEMBL8908771 | 0.76 | ACE (0.61) | ACEPOLBTDP1L3MBTL1CHEK1 | |
| SCHEMBL4573235 | 0.76 | ACE (0.61) | ACEPOLBTDP1L3MBTL1CHEK1 | |
| SCHEMBL3840630 | 0.76 | ACE (0.61) | ACEPOLBTDP1L3MBTL1CHEK1 | |
| SCHEMBL31494183 | 0.75 | KEAP1 (0.62) | DPP4DPP8POLBTDP1PARP1 | |
| SCHEMBL26255929 | 0.75 | KEAP1 (0.62) | DPP4DPP8POLBTDP1PARP1 | |
| SCHEMBL11350319 | 0.74 | ACE (0.59) | ACEPOLBTDP1PREPL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531204-B1 | TEMPLATE - FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| US-8629112-B2 | Template-fixed peptidomimetics with CXCR7 modulating activity | POLYPHOR AG (CH) | 2014-01-14 | — | — | US | disclosed |
| US-20130023483-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2013-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023483-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | CXCR1, CXCL12, CXCR6 | ACE 1822/4885DPP4 1263/4885DPP8 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.