Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14631713 | 0.87 | EPHX2 (0.35) | NR4A1NR4A2NR4A3TAS2R14PTGS1 | |
| SCHEMBL14631716 | 0.87 | EPHX2 (0.35) | NR4A1NR4A2NR4A3TAS2R14PTGS1 | |
| SCHEMBL14635871 | 0.80 | CA1 (0.42) | MAPTGAACYP2C19CYP1A2CYP2C9 | |
| SCHEMBL14636485 | 0.80 | MAPT (0.37) | TAS2R14NPSR1MAPTXBP1KDM4E | |
| SCHEMBL138245 | 0.74 | TAS2R14 (0.39) | TAS2R14CYP1A1CYP1B1NPSR1MAPT | |
| SCHEMBL16957940 | 0.74 | PTGS1 (0.39) | TAS2R14PTGS1NPSR1MAPTXBP1 | |
| SCHEMBL28374357 | 0.74 | TAS2R14 (0.35) | TAS2R14PTGS1CYP1A1CYP1B1NPSR1 | |
| SCHEMBL28233842 | 0.73 | EIF2AK2 (0.47) | NR4A1NR4A2NR4A3TAS2R14CYP1A1 | |
| SCHEMBL8028621 | 0.73 | KDM4E (0.60) | NR4A1NR4A2NR4A3PTGS1CYP1A1 | |
| SCHEMBL31064612 | 0.71 | CES2 (0.50) | TAS2R14NPSR1MAPTXBP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010880-A1 | NEW CRTH2 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2013-01-24 | — | — | WO | disclosed |